Yes! When you configure your web app you need to use the HTML home page as Web app domain URL for your target web site.
Please be careful to configure the Root URL. If you set it as https://www.someurl.com, all request will be redirected to the URL prefixed with https://www.someurl.com; if you set as https://www.someurl.com/path1, all requests will be redirected to the URL prefixed with https://www.someurl.com/path1. Recommend approach is only set domain name (ex. www.someurl.com) as Root URL.